What should you not do with time-release capsules?

• A. Take with water
• B. Open and sprinkle on foods
• C. Store in a refrigerator
• D. Crush or mix with foods

Answer: (D)

Time-release capsules are designed to release medication slowly over time. Crushing or mixing the contents with foods destroys that release mechanism, causing the drug to be released all at once. This can lead to a sudden surge in drug levels, increasing the risk of serious side effects or overdose and negating the intended duration of action. So, never crush or open a time-release capsule or mix its contents with foods. Swallow the capsule whole with water as directed. Storage conditions (like refrigeration) depend on the specific medicine and its labeling, so follow those instructions.